Molecular Targets in Protein Misfolding and Neurodegenerative Disease
By:Pierfausto Seneci
Published on 2014-10-07 by Academic Press
Aimed at |drug discoverers| – i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular – the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases Provides a “drug discovery application oriented perspective, evaluating targets and candidates for their overall therapeutic potential Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets
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Book ID of Molecular Targets in Protein Misfolding and Neurodegenerative Disease's Books is 4lICBAAAQBAJ, Book which was written byPierfausto Senecihave ETAG "9URkbdseqJQ"
Book which was published by Academic Press since 2014-10-07 have ISBNs, ISBN 13 Code is 9780128004999 and ISBN 10 Code is 0128004991
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